Tuesday, October 22, 2013

Practical aspects of the novel oral anticoagulants

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Here's some more info form a review in CCJM.
Monday, October 21, 2013

Biphosphonates and the risk of atrial fibrillation

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From a recent study in Chest: Results: Six observational studies (n = 149,856) and six RCTs (n = 41,375) were included for analysis. On ...
Sunday, October 20, 2013

Pharmacologic treatments in ARDS

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Neuromuscular blocking agents, corticosteroids and nitric oxide, among other agents, are discussed in this review . The use of neuromuscular...
Saturday, October 19, 2013

The use of biomarkers to guide antimicrobial therapy

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Many biomarkers have been looked at. For adult hospitalized patients procalcitonin is the most promising. An evidence summary is contained...
Thursday, October 17, 2013

Dietary determinants of incident DM 2

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Diets characterized by high Mediterranean diet score and low glycemic load were beneficial in this study .
Tuesday, October 15, 2013

CT calcium scoring: who and when?

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There are a couple of good articles on this topic in a recent issue of CCJM ( here and here ). CT calcium scoring has been widely misunders...
Monday, October 14, 2013

Borrelia miyamotoi

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---causing an illness resembling human granulocytic anaplasmosis .

Anterior precordial lead ST segment depression in inferior STEMI

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Dr. Smith discusses such a case in his ECG blog. He makes some teaching points on various aspects of the case. Concerning the anterior pr...
Sunday, October 13, 2013

Universal acetaminophen level screening on all overdoses?

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It's easy enough to do but how helpful is it? Results in the literature are mixed. The number needed to screen, depending on the popul...
Saturday, October 12, 2013

What happened to unstable angina?

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Braunwald and Morrow ask this question in a recent review in Circulation. It seems we’ve gone full circle: It appears that we have no...
Friday, October 11, 2013

The HDL controversy

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This issue was reviewed recently in Cirulation. The HDL story is not over. Some of the points of the review: The epidemiologic associatio...
Thursday, October 10, 2013

Postural tachycardia syndrome (POTS)

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Recent review in Circulation, free full text.
Wednesday, October 09, 2013

PFO closure for stroke prevention: how does the evidence add up?

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Three RCTs had failed to show benefit, so a meta-analysis was done and recently published: Results Three RCTs met inclusion criteria. T...
Tuesday, October 08, 2013

Management of acute pancreatitis: can we be evidence based?

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Evolving concepts and controversies are addressed in a recent review published in the Cleveland Clinic Journal of Medicine. The article is...
Monday, October 07, 2013

FFP versus 4 factor PCC for warfarin reversal

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4 factor PCC was associated with faster INR reversal, a lower red cell transfusion requirement and a better safety profile in this study . N...
Sunday, October 06, 2013

Treatment of ventricular arrhythmias in the post-CAST era: beyond device therapy

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Some take home points from a recent review : The CAST study changed our thinking about drug treatment of ventricular arrhythmias but it did...
Saturday, October 05, 2013

Renal Denervation as a treatment for resistant hypertension

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This is gaining enthusiasm, devices are proliferating and research is ongoing. Free full text review here via Medscape. More data are nee...
Friday, October 04, 2013

More information on azithromycin and the risk of sudden cardiac death

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This CCJM review covers many of the same points I recently blogged here .
1 comment:

The role of obesity in atrial fibrillation

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Atrial fibrillation is increasingly being recognized as a disease of obesity and the metabolic syndrome. A nice review (free full text) on...
Thursday, October 03, 2013

Systemic sclerosis review

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This review , available in free full text from Mayo Clinic Proceedings, is the best I've seen on this topic. Points I found interesting...