Wednesday, July 30, 2014

Physical activity and the metabolic syndrome

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Another reminder, from a review : Physical activity has favorable effects on all components of the metabolic syndrome and on the resulting...
Tuesday, July 29, 2014

Meta-analysis of prone ventilation for severe ARDS

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From the paper : Data Synthesis:This analysis included 11 randomized controlled trial, 2,246 total adult patients, and 1,142 patients vent...
Monday, July 28, 2014

How low can you go? Evaluating the trigger for a restrictive transfusion strategy

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From a recent systematic review and meta-analysis : Results In the primary analysis, pooled results from 3 trials with 2364 participants...
Sunday, July 27, 2014

SARS versus MERS

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From a recent review : Recent findingsBats are the natural reservoirs of SARS-like coronaviruses (CoVs) and are likely the reservoir of ME...
Saturday, July 26, 2014

Effect of a transitions program on readmission

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From AJHSP : Results Over the 2-year study period, 19,659 unique patients had 26,781 qualifying index admissions, 2,523 of which resulted ...

Uric acid as a risk factor for erectile dysfunction

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In this study there was a two fold increase in risk of ED for every 1 mg/dL increase in uric acid. HT to Clinical Cases and Images .
Thursday, July 24, 2014

IVC filters for patients with unstable pulmonary embolism

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PE of such severity that another one is likely to be fatal has been a popular, though not strictly evidence based, indication for IVC filter...
Wednesday, July 23, 2014

Sedation in mechanically ventilated patients

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Here's a trial comparing daily interruption of continuous infusion sedation with prn sedation. From the study: Methods Adult patie...
Tuesday, July 22, 2014

Impact of a multidisciplinary sepsis team

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Improved time to antibiotic delivery in this study . The team included a member of the pharmacy staff. Via Hospital Medicine Virtual Journa...
Monday, July 21, 2014

Statin administration for the prevention of contrast induced nephropathy: is it the real deal or will it go the way of acetylcysteine?

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Here are two studies from JACC that look promising. [ 1 ] [ 2 ]
Sunday, July 20, 2014

Disappointing results for ICU telemedicine

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From a recent study : Design, Setting, and Participants   Observational pre-post study of patients treated in 8 “intervention” ICUs (7 hos...
Saturday, July 19, 2014

Transfusion thresholds and the risk of hospital associated infections

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Interesting findings from a recent meta-analysis : Data Extraction and Synthesis Twenty-one randomized trials with 8735 patients met eli...
Friday, July 18, 2014

Update on vena caval filters

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Here's a recent review . The review covers both SVC and IVC filters. SVC filters Upper extremity DVT has a relatively low risk of causi...
Wednesday, July 16, 2014

Work up and secondary prevention after ischemic stroke

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Here is an excellent free full text review in Circulation. A few important points from the review: Initial imaging localizes the ischemic l...
Tuesday, July 15, 2014

Stanford Medicine 25

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A teaching web site and blog dedicated to the culture of bedside medicine. Great educational content.
Monday, July 14, 2014

Effects of target specific (novel) oral anticoagulants on the coag assays

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Quantitative monitoring or TSOACs is not available in most community hospitals nor is it necessary. Nevertheless some knowledge of the qual...
Sunday, July 13, 2014

Type B lactic acidosis

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A nice discussion over at Renal Fellow Network . Classically, Type A lactic acidosis is related to tissue hypoperfusion resulting in an in...
Saturday, July 12, 2014

TNF inhibitors: what the hospitalist needs to know

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Free full text from CCJM .
Friday, July 11, 2014

New oral anticoagulants in the treatment of DVT and PE

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This editorial contains a rundown of the phase III trials for all four agents that have been studied. It is available as free full text. ...
Thursday, July 10, 2014

Remember thrombotic storm?

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A while back I blogged about this condition . It's essentially what the name implies. There is no known single substrate nor is there a...