Thursday, June 30, 2016

Proton pump inhibitors and eosinophilic esophagitis

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The question is addressed in this paper . Although EO is in general unresponsive to PPIs there is a subset that is: ...
Wednesday, June 29, 2016

Treatment of eosinophilic esophagitis

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From a recent review : If left untreated, eosinophilic inflammation induces fibrosis, angiogenesis and stricture fo...
Tuesday, June 28, 2016

Painful LBBB syndrome

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A paper here describes this rarely encountered entity.
Monday, June 27, 2016

Lifestyle intervention, weight loss and atrial fibrillation incidence in type 2 diabetes

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From the Look AHEAD trial : A total of 5,067 overweight or obese individuals 45 to 76 years old with type 2 diabetes...

Fluid overload after fluid resuscitation

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It happens and may be unavoidable. Strategies to deal with it in the post resuscitation period are needed. Review here .
Sunday, June 26, 2016

Environmental etiologic factors for eosinophilic esophagitis

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Like many chronic conditions EO represents an interaction between genetics and environment. From a recent review : ...
Saturday, June 25, 2016

Mineralocorticoid excess and related syndromes

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This was the topic of a recent review in Advances in Chronic Kidney Disease. Below are some take home points. Hyper...
Friday, June 24, 2016

Premature ventricular contractions: everything you wanted to know and more

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A detailed review was recently published, which should be read in the original. Below are a few key issues covered. Mechani...
Thursday, June 23, 2016

Vagal atrial fibrillation

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This entity has long been known. It represents one group of mechanisms accounting for the increased risk of atrial fib with ...
Wednesday, June 22, 2016

How should we define valvular and non-valvular atrial fibrillation?

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When the NOACs were first introduced atrial fibrillation associated with any hemodynamically significant valvular disease was...
Tuesday, June 21, 2016

Walking speed, walking distance and mortality

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From a recent review : Although treadmill exercise testing can provide an assessment of cardiorespiratory fitness, w...
Monday, June 20, 2016

Giving vasoactive drugs through a peripheral IV

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Controversy exists as to whether vasopressors can be given through a peripheral IV and practices vary from institution to ins...
Sunday, June 19, 2016

Weight reduction, pericardial adipose tissue and cardiac structure in patients with atrial fibrillation

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From a recent study : Methods We prospectively performed cardiac magnetic resonance imaging on 87 participan...
Saturday, June 18, 2016

Measles and pertussis risk related to vaccine refusal

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From a JAMA report : Conclusions and Relevance A substantial proportion of the US measles cases in the era after el...
Friday, June 17, 2016

Legionnaires' disease review

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This topic was recently reviewed in Lancet . From the summary and introduction: Since first identified in ea...
Thursday, June 16, 2016

The internist as both specialist and generalist

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Here's a quote from William Osler that explains why: There are, in truth, no specialties in medicine, since to ...
Wednesday, June 15, 2016

HIT and the spectrum of thrombocytopenia in the ICU

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Here’s a great review from last December. Some key points: HIT is a state of extreme hypercoagulability. Over 50% of patients ...
Tuesday, June 14, 2016

Left atrial appendage occlusion for stroke prevention in atrial fibrillation

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From a recent review : A single device has now received regulatory approval for patients at increased risk of stroke...
Monday, June 13, 2016

Clinical features of hairy call leukemia

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Think of it when you see pancytopenia (or bicytopenia) and splenomegaly without peripheral lymphadenopathy. From a recent re...
Sunday, June 12, 2016

Eosinophilic esophagitis as an atopic disease

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From a recent review : Eosinophilic Esophagitis (EoE) is a classic atopic disease as it shares features with other a...