Sunday, May 07, 2017

Cardiocerebral syndrome

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This refers to cognitive dysfunction occurring in heart failure. It has been referred to in various ways through the years. I first ...
Saturday, May 06, 2017

Wireless LV endocardial pacing takes CRT to the next level

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The SELECT-LV Study, reporting results of the WiSE-CRT system (EBR Systems, Sunnyvale, California) was recently published in...
Friday, May 05, 2017

Yes Virginia, LDL really does matter

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Numerous authors over the last several years, citing the pleiotropic effects of statins, have refused to believe that LDL red...
Thursday, May 04, 2017

“Early” invasive versus selectively invasive strategy for non ST segment ACS

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Here is the paper in question. I put the word early in quotes because it meant cath within 48 hours, not an immediate cath....
Wednesday, May 03, 2017

NEJM review of Cushing’s syndrome

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Some key points from the review follow: Prior to the obesity epidemic assessment of the pretest probability of Cushing’s syndrome b...
Tuesday, May 02, 2017

Periprocedural management of anticoagulation in non-valvular a fib: what the hospitalist needs to know

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This expert consensus decision pathway is available as free full text here . It is in line with published guidelines and oth...
Monday, May 01, 2017

Carcinoids and other neuroendocrine tumors

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This review in the Archives of Pathology and Laboratory Medicine helps clarify the sometimes confusing terminology around th...
Sunday, April 30, 2017

Giant cell myocarditis review

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Here is a free full text review . A few points of interest form the paper: Historically, GCM and cardiac sar...
Saturday, April 29, 2017

The Coombs test: some things you need to know

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A nice free full text review in the Archives of Pathology and Laboratory Medicine.
Friday, April 28, 2017

Review of carcinoid heart disease

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The full text of this review is available only by subscription, but the audio summary is open access. Here are a few...

Chronic calcium blocker use and reduced mortality in sepsis

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From a recent paper : Abstract Objectives: Experimental studies suggest that calcium channel blockers can im...

Update on the clinical and pathologic aspects of ANCA diseases

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Free full text review .
Saturday, March 25, 2017

Video laryngoscopy for for endotracheal intubation: better visualization but not better outcomes

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Recent study here .
Friday, March 24, 2017

Vancomycin in combination with zosyn increased the risk of AKI

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--- according to this systematic review and meta-analysis . The authors concluded: Increased AKI with concomitant ...
Thursday, March 23, 2017

Type of atrial fibrillation and stroke risk

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From a recent paper : Background—Whether the pattern of atrial fibrillation (AF) modifies the risk/benefit of antico...
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Wednesday, March 22, 2017

Hypotension due to IV acetaminophen

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From a recent paper published in Critical Care Medicine: Objectives: We sought to assess the incidence of acetamino...
Tuesday, March 21, 2017

Treatment decisions for patients with a first seizure

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Here is a guideline synopsis published in JAMA. From the article: Major recommendations Whether to initiate immed...
Monday, March 20, 2017

Therapeutic hypothermia after in hospital cardiac arrest

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There have been no RCTs looking at induced hypothermia following in hospital arrest. The 2010 ACLS guidelines recommended hy...
Sunday, March 19, 2017

The patient safety movement: how are we doing?

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According to the authors of a recent viewpoint article in JAMA , although the decade following the Institute of Medicine Repo...
Saturday, March 18, 2017

The EMPIRICUS trial

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From a recent issue of JAMA : Question Does empirical antifungal therapy increase invasive fungal infection–free s...