Wednesday, May 31, 2017

Low dose TPA for stroke??

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Published in NEJM: Background Thrombolytic therapy for acute ischemic stroke with a lower-than-standard...
Tuesday, May 30, 2017

Pulmonary manifestations of connective tissue diseases

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This post is drawn from a BMJ review which is one of the best I've seen on the topic. Though titled Management of inters...
Saturday, May 27, 2017

Timing of the first epinephrine dose in patients with shockable rhythm cardiac arrest

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Popular usage of epinephrine is in cardiac arrest (CA) is early---often after the first shock in VF/pulseless VT arrest. Wha...
Friday, May 26, 2017

Encephalopathy secondary to metronidazole

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Here is a case presentation and brief discussion in NEJM ( free full text ). From the paper: Encephalopathy associa...
Thursday, May 25, 2017

Dabigatran versus warfarin and the risk of AKI

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From a recent paper : Background Whether dabigatran is associated with a lower risk of acute kidney injury (AKI) in...

The future of CME

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A NEJM Perspective piece on this topic opened with: The point at which a clinician takes ownership of his or her o...
Wednesday, May 24, 2017

Viewpoint article in JAMA issue devoted to conflicts of interest

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The article is available here as free full text. Here are a few points of interest. Early on in the piece the autho...
Tuesday, May 23, 2017

Guidelines for the use of bedside echo in critically ill patients

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Published here .
Monday, May 22, 2017

Bariatric surgery reduces the risk of atrial fibrillation

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From a recent paper in JACC .
Sunday, May 21, 2017

Anticoagulant related nephropathy: huge problem, hugely under-recognized

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From a commentary in JACC, here are some key points. What is it? Anticoagulant related nephropathy (ARN) i...
Saturday, May 20, 2017

Predicting ARDS mortality based on a simple clinical score

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From a paper in Critical Care Medicine: Objectives: Although there is general agreement on the characteristic feat...
Friday, May 19, 2017

Antiarrhythmic drugs in cardiac arrest: should amiodarone be moved up two shocks? Is lidocaine the winner by a slim margin?

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This trial , published in NEJM, has been the subject of numerous social media posts. The popular spin is that this is just a...
Thursday, May 18, 2017

Ganglionic plexus ablation for atrial fibrillation: disappointing results

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This paper in JACC introduces another category in the classification of atrial fibrillation: advanced AF. From the paper...
Wednesday, May 17, 2017

Alcohol intake and the risk of atrial fibrillation

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Although there is a well known “U shaped” curve describing the relation between the amount of intake and overall cardiovascul...
Tuesday, May 09, 2017

No definite association between testosterone replacement and VTE

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---in low to moderate risk patients in this study .
Monday, May 08, 2017

What is the best oxygen target for critically ill patients?

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From a recent study published in JAMA : Question Among critically ill patients, is a conservative oxygenation stra...