Cochrane review on gabapentin for neuropathic pain
This Cochrane review is abstracted in the February 1 issue of American Family Physician. Gabapentin is effective with a number needed to treat (NNT) of 4. Adverse effects including dizziness, somnolence and headache occur with a number needed to harm (NNH) of 4. This is a significant trade off which must be gauged by patient preference. Tricyclics and carbamazepine have lower NNTs and are less expensive.
Can the gabapentin be used alone, or will it need to be combined with other drugs in order to be effective?
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