Methods: We sought to determine if the presence of at least one PAC would predict AF and at least one PVC would predict HF using a single standard (10-second) ECG ...
Results: Among 5,577 CHS participants followed for a median 12 years, a 12-lead ECG PAC (4%) was associated with 60% increased risk of AF (HR 1.6; 95% CI 1.3-2.0; P less than 0.001; Figure) and a PVC (5%) with a 30% increased risk of HF (HR 1.3; 95% CI 1.0-1.6; P = 0.021) and a decline in left ventricular ejection fraction (OR 2.8, 95% CI 1.3-6.1, p=0.008) after multivariable adjustment...
Conclusions: Based on a single standard ECG, the presence of any atrial ectopy predicted AF and any ventricular ectopy predicted HF.
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