BACKGROUND: Imaging
use in the diagnostic workup of pulmonary embolism (PE) has increased
markedly in the last 2 decades. Low PE prevalence and diagnostic
yields suggest a significant problem of overuse.
PURPOSE: The purpose
of this systematic review is to summarize the evidence associated
with the interventions aimed at reducing the overuse of imaging in
the diagnostic workup of PE in the emergency department and hospital
wards.
DATA SOURCES:
PubMed, MEDLINE, Embase, and EBM Reviews from 1998 to March 28, 2017.
STUDY SELECTION:
Experimental and observational studies were included. The types of
interventions, their efficacy and safety, the impact on healthcare
costs, the facilitators, and barriers to their implementation were
assessed.
DATA SYNTHESIS:
Seventeen studies were included assessing clinical decision support
(CDS), educational interventions, performance and feedback reports
(PFRs), and institutional policy. CDS impact was most comprehensively
documented. It was associated with a reduction in imaging use,
ranging from 8.3% to 25.4%, and an increase in diagnostic yield,
ranging from 3.4% to 4.4%. The combined implementation of a CDS and
PFR resulted in a modest but significant increase in the adherence to
guidelines. Few studies appraised the safety of interventions. There
was a lack of evidence concerning economic aspects, facilitators, and
barriers.
CONCLUSIONS: A
combined implementation of an electronic CDS and PFRs is more
effective than purely educational or policy interventions, although
evidence is limited. Future studies of high-methodological quality
would strengthen the evidence concerning their efficacy, safety,
facilitators, and barriers.
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