Highlights
In some centers,
all Diabetic Ketoacidosis (DKA) patients are admitted to ICU.
No difference in
in-hospital mortality was found between DKA patients admitted to
step-down units or ICU.
DKA patients
admitted to step-down units had significantly lower costs than those
admitted to ICU.
Hospitals should
preferentially consider monitoring of DKA patients in step-down
units.
Abstract
Purpose
There is wide
variation in the utilization of Intensive Care Unit (ICU) beds for
treatment and monitoring of adult patients with Diabetic Ketoacidosis
(DKA). We sought to compare the outcomes and hospital costs of adult
DKA patients admitted to ICUs as compared to those admitted to
step-down units.
Materials and
methods
We included
consecutive adult patients from two hospitals with a diagnosis of
DKA. Patients were either admitted to the ICU, or a step-down unit,
which has a nurse-to-patient ratio of 2:1, but does not have
capability for mechanical ventilation or administration of vasoactive
agents. The primary outcome was in-hospital mortality.
Results
We included 872
patients in the analysis. 71 (8.1%) were admitted to ICU, while 801
(91.9%) were admitted to a step-down unit. We found no difference in
in-hospital mortality between patients admitted to the ICU and those
admitted to the step-down unit (adjusted odds ratio [OR]: 1.14, 95%
confidence interval [CI]: 0.87–2.64). Mean total hospital costs
were significantly higher for patients admitted to the ICU ($20,428
vs. $6484, P less than 0.001).
Conclusions
Adult DKA patients
admitted to a step-down unit had comparable in-hospital mortality and
lower hospital costs as compared to those admitted to the ICU.
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