Saturday, March 30, 2019

Do you really need a TSH receptor antibody test to distinguish Grave’s disease from other forms of hyperthyroidism?

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In this study clinical assessment alone was poor .
Friday, March 29, 2019

Low vitamin D levels associated with increased mortality

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From a recent study published in Mayo Clinic Proceedings : Objective To determine the relationship between 2...

Testosterone replacement associated with better cardiovascular outcomes

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Will a randomized controlled trial some day blow this out of the water like we saw in the case of ERT ?

Troponin elevation in stroke may point to a cardioembolic etiology

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From a recent paper : Abstract Background Our aim was to determine whether patients with embolic strokes of ...
Thursday, March 28, 2019

Appropriateness of troponin ordering in the hospital

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Form a recent study : Troponin assays are integral to the diagnosis of acute myocardial infarction (AMI), but there ...

Triple antibiotic therapy against carbapenemase producing bacteria

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Here is a review on the topic. These regimens have been our go-to for a while now and are effective although the crude mort...

Targeted temperature management post arrest: how long?

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Findings from a recent trial : Question Does targeted temperature management at 33°C for 48 hours result in better neurologic ...
Wednesday, March 27, 2019

Vitamin C deficiency as a cause of pulmonary hypertension

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A dramatic case report of this previously known entity .

Hospitalization rates and lengths of stay for VTE in Alberta Canada

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Since 2002 they have been sending a fair number of patients home from ER or clinic but once hunkered in patients stay awhile and these num...

In non malignant pleural effusions transudates may have a worse prognosis than exudates

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Probably due to their association with other-organ failures .
Tuesday, March 26, 2019

Adjuvant metolazone (zaroxalin) in loop diuretic refractory patients

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Resist the temptation to add the “big Z” according to this study .

Hepatic encephalopathy update

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From a recent review : Hepatic encephalopathy is a state of brain dysfunction resulting from decompensation of cirrh...

The adverse effects of CPOE on ER throughput

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Discussion at SGEM and primary source .

Can voice patterns give away your risk of CAD?

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Yes, but special instruments are required .

Is thrombophilia testing helpful?

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Maybe in very restricted circumstances but not to determine the duration of anticoagulation after VTE .
Monday, March 25, 2019

Checking urine eosinophils to evaluate for acute interstitial nephritis

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I agree this is one we should probably just stop doing . Not that it’s costing a lot of money or harming patients, but, desp...

Growing evidence challenges conservative transfusion dogma

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The last few years have seen quite a push toward restrictive transfusion strategies with conservative hemoglobin (less than s...

Thrombocytopenia developing in hospitalized patients

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Here’s a nice review .

What the hospitalist needs to know about the TTP-HUS spectrum

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This is the best review I’ve ever seen on this. Free full text .
Saturday, March 23, 2019

Be careful using a restrictive transfusion strategy in patients with cardiovascular disease

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From a recent review : There is biological plausibility that patients with CVD may benefit from higher transfusion t...