Surgery in patients taking new (target specific) oral anticoagulants

From a recent review in CCJM:

While various periprocedural protocols for TSOAC therapy have been proposed, evidence-based guidelines are still to come.

The article summarizes the current thinking. It gives a nice summary of the pharmacokinetics and pharmacodynamics, and practical information for the perioperative period. A guide for timing of discontinuation of TSOACs prior to surgery is found in this table.