when it has no physiologic or pharmacologic plausibility in the first place? This is a distortion of evidence based medicine which takes empiricism to an extreme. Straight from the Doc, Medpundit and Medicine and Man have already pointed us to the Lancet article on the subject.
This overview from Homeowatch outlines the field’s history and states that homeopathy was harmless compared to prevailing nineteenth century conventional medical practices, a fact which drove its popularity. It points out the utter irrationality of the theory, which is that a “spirit like essence” remains behind in the water even after all molecules of active substance have been diluted out.
Total lack of biologic plausibility is one reason not to bother to study homeopathy. Another reason, as has already been pointed out by the other bloggers, is that the adherents won’t believe the studies. At least some don’t believe a randomized placebo controlled trial is the proper methodology.
If you want to debunk something, rather than spend all that money on studies, why not just call Randi the magician?