Friday, March 03, 2006
Cochrane review on gabapentin for neuropathic pain
This Cochrane review is abstracted in the February 1 issue of American Family Physician. Gabapentin is effective with a number needed to treat (NNT) of 4. Adverse effects including dizziness, somnolence and headache occur with a number needed to harm (NNH) of 4. This is a significant trade off which must be gauged by patient preference. Tricyclics and carbamazepine have lower NNTs and are less expensive.
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1 comment:
Can the gabapentin be used alone, or will it need to be combined with other drugs in order to be effective?
John
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