Monday, January 28, 2008

Glycemic control, crystaloid vs colloid debates remain unsettled

The SepNet investigators recently reported their two by two factorial trial in NEJM. Intensive glycemic control (112 mg/dl vs 151 mg/dl) was not associated with improved mortality or organ failure scores but was associated with more severe hypoglycemia and other adverse effects. Pentastarch was compared with modified RL and was associated with increased renal failure.

Retired Doc comments here.

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