The atherogenic lipid phenotype (ALP)
---is a major cause of residual cardiovascular risk after statin treatment “to goal.” Treatment options are discussed in this review:
Large outcome trials designed to assess the value of combining statins with other agents to target HDL cholesterol and non-HDL cholesterol will not be completed for a few years, but there is ample evidence for the clinician to consider combination therapy. The choices for therapies to supplement statins include niacin, fibrates, and omega-3 fatty acids.
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