This one looked at patients with prior MI although multiple studies have shown hazards in patients with and without prior cardiovascular disease.
In the conclusion the authors make the strongest statement yet:
Even short-term treatment with most NSAIDs was associated with increased risk of death and recurrent MI in patients with prior MI. Neither short- nor long-term treatment with NSAIDs is advised in this population..
I've harped on this before emphasizing that they're all dangerous, not just Vioxx.
Via Dr. John M.
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