A great post at The Kidney Doctor talks about NSAID risks and asks why doctors don't get it. It summarizes the adverse renal effects of NSAIDs and links to an article documenting the degree of NSAID use among CKD patients, both over the counter and by prescription.
I would take the discussion a step further and ask why the FDA doesn't get it. Their inconsistency is remarkable. After all for more harm is attributable to NSAIDs than to poor old Darvocet.
The post describes long term NSAID use in CKD patients. But let's not forget the harm caused by only occasional use of NSAIDs in healthy individuals.