Results of two trials were presented at AHA.
In this one 33 C was no better as a therapeutic target than 36 C in terms of survival or neurologic outcome.
In the other study initiation of cooling pre-hospital was associated with greater incidence or re-arrest and need for diuretics but produced no survival or neurologic benefit.
Based on a related discussion at Medpage Today therapeutic hypothermia remains an important intervention. However we have yet to find the sweet spot in terms of optimal timing and “dose” of the intervention.