Being on a statin was associated with a higher likelihood of survival following in hospital cardiac arrest

From a poster presentation at AHA 2016:

Methods: A retrospective analysis of consecutive hospitalized patients that underwent CPR between 4/2012 to 12/2013 at Beaumont Hospital. Patients with CPR perioperatively, in the setting of trauma, during pregnancy and postpartum were excluded, also patients or their surrogates who elected palliative care/hospice were excluded. Univariable and a step-down logistic regression multivariable analysis were performed…

Pre-arrest clinical factors and CPR characteristics associated with survival on univariable analysis were: History of PCI in 36.4% of survivors compared to 16.5% of those who did not survive (p=0.013). Hyperlipidemia was more common in survivors (68.2% versus 32.5%, p=0.001), as well as being on statins (76.7% versus 43%, p=0.0004). Those who did not survive were more likely to have active cancer (16.3% versus 2.3%, p=0.018), less likely to have a shockable rhythm (7.9% versus 27.9%, p=0.003), and more likely to have CPR greater than or equal to 15 minutes (82.4% versus 19.5%, p less than 0.0001). On multivariable analysis, CPR duration and statin therapy were the only factors associated with survival. Those who did not survive were more likely to have CPR greater than or equal to 15 minutes (Adjusted OR 18.08, 95% CI 6.5-50.5, p less than 0.001) and less likely to be on statin therapy before cardiac arrest ( Adjusted OR 0.29, 95% CI : 0.10-0.83 p= 0.021) with C-Statistic of 0.86.