Heavy cannabis use: bad for bone health

From the green journal:

The effects of cannabinoids on bone mass and bone turnover in humans are unknown.

Using a cross-sectional study design we found that heavy cannabis use is associated with low body mass index, high bone turnover, low bone density, and an increased risk of fracture.

Heavy cannabis use has a detrimental effect on bone health by a direct effect on the skeleton and an indirect effect mediated by low body mass index.