From a recent review:
Distal (or calf) DVT is a very common medical condition, representing half of all diagnosed DVTs.
The diagnostic performances of venous compression ultrasound are lower for the diagnosis of distal DVT compared to proximal DVT.
All patients with distal DVT do not necessarily require anticoagulant treatment.
Low-risk outpatients may benefit from ultrasound surveillance alone, without any anticoagulation.
In high-risk patients, such as inpatients, patients with cancer or previous DVT, therapeutic anticoagulation is recommended.
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