Artificial elevation of the serum creatinine can occur due to interfering substances. An under-appreciated cause is DKA, in which acetone and acetoacetate cause overestimation of the creatinine concentration. The typical finding is a mild elevation of serum creatinine on presentation with DKA which clears within a matter of hours. This is often mistaken for mild acute renal insufficiency which quickly resolves with fluid resuscitation.
Via Renal Fellow Network.
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