Wednesday, September 12, 2018

Advanced dementia patients do better when their broken hips are repaired


From a recent paper in JAMA Internal Medicine, here are the data:

Importance The decision whether to surgically repair a hip fracture in nursing home (NH) residents with advanced dementia can be challenging.

Objective To compare outcomes, including survival, among NH residents with advanced dementia and hip fracture according to whether they underwent surgical hip fracture repair.

Design, Setting, and Participants We conducted a retrospective cohort study of 3083 NH residents with advanced dementia and hip fracture, but not enrolled in hospice care, using nationwide Medicare claims data linked with Minimum Data Set (MDS) assessments from January 1, 2008, through December 31, 2013.

Methods Residents with advanced dementia were identified using the MDS. Medicare claims were used to identify hip fracture and to determine whether the fracture was managed surgically. Survival between surgical and nonsurgical residents was compared using multivariable Cox proportional hazards with inverse probability of treatment weighting (IPTW). All analyses took place between November 2015 and January 2018. Among 6-month survivors, documented pain, antipsychotic drug use, physical restraint use, pressure ulcers, and ambulatory status were compared between surgical and nonsurgical groups.

Results Among 3083 residents with advanced dementia and hip fracture (mean age, 84.2 years; 79.2% female [n = 2441], 28.5% ambulatory [n = 879]), 2615 (84.8%) underwent surgical repair. By 6-month follow-up, 31.5% (n = 824) and 53.8% (n = 252) of surgically and nonsurgically managed residents died, respectively. After IPTW modeling, surgically managed residents were less likely to die than residents without surgery (adjusted hazard ratio [aHR], 0.88; 95% CI, 0.79-0.98). Among 2007 residents who survived 6 months, residents with surgical vs nonsurgical management had less docmented pain (29.0% [n = 465] vs 30.9% [n = 59]) and fewer pressure ulcers (11.2% [n = 200] vs 19.0% [n = 41]). In IPTW models, surgically managed residents reported less pain (aHR, 0.78; 95% CI, 0.61-0.99) and pressure ulcers (aHR, 0.64; 95% CI, 0.47-0.86). There was no difference between antipsychotic drug use and physical restraint use between the groups. Few survivors remained ambulatory (10.7% [n = 55] of surgically managed vs 4.8% [n = 1] without surgery).

Conclusions and Relevance Surgical repair of a hip fracture was associated with lower mortality among NH residents with advanced dementia and should be considered together with the residents’ goals of care in management decisions. Pain and other adverse outcomes were common regardless of surgical management, suggesting the need for broad improvements in the quality of care provided to NH residents with advanced dementia and hip fracture.

But now take a look at how JAMA Internal Medicine spun the data!

Key Points

Question Do outcomes for nursing home residents with advanced dementia and hip fracture differ with vs without surgical repair?

Findings In this cohort study of 3083 nursing home residents with advanced dementia and hip fracture, over 2-year follow-up, the mortality rate was 12% lower in residents whose hip fracture was treated with surgery. Among 6-month survivors, pain, antipsychotic drug use, physical restraint use, pressure ulcers, and loss of ambulation were common regardless of surgical management.

Meaning In nursing home residents with advanced dementia and hip fracture, the potential survival benefit of surgery should be considered together with the patients’ goals of care; there is an opportunity to improve quality of care regardless of how the fracture is managed.


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