Antipsychotics cause Q-Tc interval prolongation at a higher rate than do antidepressants, and the typical antipsychotics thioridazine, pimozide, and i.v. haloperidol all have the highest potential for Q-Tc interval prolongation. Tricyclic antidepressants have a higher rate of Q-Tc interval prolongation than do SSRIs, particularly at higher concentrations and in overdose situations.
Safety monitoring recommendations are given.
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