Reports in the last few years highlight the emerging importance of lead aVR, a long neglected electrocardiographic lead. I have written several posts on the important clues available from lead aVR in the detection of left main or multivessel coronary ischemia, the differential diagnosis of narrow complex tachycardias, the differentiation between VT and SVT with aberrancy, and pericarditis. All these and more are summarized in this quick reference guide, from the Paucis Verbis series at Academic Life in Emergency Medicine.