Saturday, March 23, 2013

Precedex for ethanol withdrawal??

Here's a nice reference.

A few observations:

It is supported only by low level evidence.

It is off label.

It appears to be safe and is gaining popularity.

It harks back to the old trick of adjunctive use of clonidine (it's a central alpha2 agonist).

It is physiologically very appealing in those patients with hypertension and tachycardia.

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