Tuesday, December 09, 2014

Intermittent bolus versus continuous infusion PPI for high risk bleeding ulcers

This systematic review and meta-analysis found no difference and concluded:

Intermittent PPI therapy is comparable to the current guideline-recommended regimen of intravenous bolus plus a continuous infusion of PPIs in patients with endoscopically treated high-risk bleeding ulcers. Guidelines should be revised to recommend intermittent PPI therapy.

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