Saturday, December 20, 2014

Toxicologic desperation: euglycemic hyperinsulinemia and lipid rescue for calcium blocker overdose

From a case report and mini-review:

Calcium channel blockers (CCBs) drugs are widely used in the treatment of cardiovascular diseases. CCB poisoning is associated with significant cardiovascular toxicity and is potentially fatal. Currently, there is no specific antidote and the treatment of CCB poisoning is supportive; however, this supportive therapy is often insufficient.

Although this is only a single case report I thought it useful to post here because it contains a brief review of the literature and a discussion of the purported mechanisms of severe calcium blocker poisoning and the mechanisms of treatment.

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