Thursday, June 04, 2015

The QTc: unreliable in the estimation of risk for Torsade de Pointes (TdP)

This post from Emergency Medicine PharmD makes the point that heterogeneity of repolarization time within the myocardial mass is more important than the QT interval itself. The best example of this is amiodarone, notorious for prolonging the QT but with minimal risk of TdP. Reliance on the QT, even the corrected QT, is simplistic as I previously posted here.

No comments: