Wednesday, November 10, 2010

Restrictive antibiotic policies in hospitals---beware the unintended consequences

This study didn't look at clinical outcomes but restrictive policies were associated with ORs of 1.49 and 1.78, respectively, for 1 and 2 hour delays. This would be very worrisome in sepsis where the big guns are routinely used initially and where mortality increases of 7% per hour of delay have been cited.

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