From the IMPROVE-IT investigators:
Conclusions
When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit.
The trial involved
patients who had had acute coronary syndrome.
With recognition of
the powerful pleiotropic effects of statins and the promulgation of
the new statin guidelines we have all but forgotten the importance of
LDL reduction itself. This was known decades ago based on non statin
trials. Nevertheless some have recently made the unwarranted claim
that LDL reduction doesn't matter.
1 comment:
Hi Robert,
First off, I came across your site and wanted to say thanks for providing a great heart-healthy resource to the community.
I thought you might find this article helpful to your readers who are trying to lower their cholesterol, as it shows photos of what 100% of your daily value of cholesterol looks like. It’s quite shocking! http://www.healthline.com/health/high-cholesterol/daily-value
Naturally, I’d be delighted if you share this article on http://doctorrw.blogspot.com/2015/09/ezetimibe-added-to-statin-therapy-ldl.html , and/or share it with your followers on social to help them make better food choices. Either way, keep up the great work Robert!
All the best,
Nicole Lascurain | Assistant Marketing Manager
p: 415-281-3100 | e: nicole.lascurain@healthline.com
Healthline
660 Third Street, San Francisco, CA 94107
www.healthline.com | @Healthline
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