Saturday, September 05, 2015

Ezetimibe added to statin therapy: LDL matters


When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes. Moreover, lowering LDL cholesterol to levels below previous targets provided additional benefit.

The trial involved patients who had had acute coronary syndrome.

With recognition of the powerful pleiotropic effects of statins and the promulgation of the new statin guidelines we have all but forgotten the importance of LDL reduction itself. This was known decades ago based on non statin trials. Nevertheless some have recently made the unwarranted claim that LDL reduction doesn't matter.

1 comment: said...

Hi Robert,

First off, I came across your site and wanted to say thanks for providing a great heart-healthy resource to the community.

I thought you might find this article helpful to your readers who are trying to lower their cholesterol, as it shows photos of what 100% of your daily value of cholesterol looks like. It’s quite shocking!

Naturally, I’d be delighted if you share this article on , and/or share it with your followers on social to help them make better food choices. Either way, keep up the great work Robert!

All the best,

Nicole Lascurain | Assistant Marketing Manager
p: 415-281-3100 | e:

660 Third Street, San Francisco, CA 94107 | @Healthline