Here is a freefull text review in the journal Cardiorenal Medicine.
Of note:
Volume expansion
with saline or bicarb based fluid is recommended for prevention of
AKI in high risk patients. Evidence suggests bicarb is superior but
the review comes short of recommending one fluid over another.
Evidence is cited in
favor of volume expansion and forced diuresis, but the review makes
no firm recommendations pending further trials.
Given the mixed
results with N-acetylcysteine its use is now considered controversial
and no recommendation was given.
Evidence favoring a
protective effect of ascorbic acid was cited but no recommendation
made.
Evidence favoring a
protective effect of statins was cited but no recommendation made.
Conspicuously absent
from the review was mention of remote ischemic preconditioning which
has shown great promise in recent studies.
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