In this study dexmedetomidine (Precedex), while comparable to midazolam (Versed) in effectiveness of sedation, was associated with less delirium and shorter time on mechanical ventilation. Here is the Medscape report on the presentation at SCCM 2009 (non-industry supported CME available).
Other popular agents for ventilator sedation, lorazepam and propofol, were not in the comparison groups.
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