Conclusions In this large, international, randomized trial, we found that intensive glucose control increased mortality among adults in the ICU: a blood glucose target of 180 mg or less per deciliter resulted in lower mortality than did a target of 81 to 108 mg per deciliter.
The Surviving Sepsis Guideline authors, aware of the lack of evidence for a specific glycemic target, made a reasonable guess at a recommendation of 150mg/dl. I think they made a pretty good guess.
(Retired Doc beat me to it with this insightful post).
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