NSAIDs and cardiovascular risk

There has been mounting evidence that the older non-selective COX inhibiting NSAIDs are just as risky to cardiovascular health as are the COX -2 inhibitors. I have linked to a number of earlier studies that bear this out. [1] [2] [3] Now there’s even more evidence of harm associated with old and new NSAIDs, published in a recent issue of the Archives of internal Medicine. In this analysis of several large registries diclofenac had the highest hazard ratio for death and MI.

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Diclofenac