Wednesday, March 11, 2009

Propofol infusion syndrome

At CHEST 2008 Mayo Clinic investigators reported 39 patients who developed propofol infusion syndrome while being treated for refractory status epilepticus. Propofol is one of a limited number of options for treatment of SE when third line treatment (for refractory SE) is necessary. The syndrome is highly fatal and the folks at Mayo have abandoned it in favor of midazolam or other alternatives.

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