Saturday, June 04, 2016

Overview of eosinophilic esophagitis


Key points from a recent paper:

General

This chronic inflammatory disease of the esophagus, once thought to be rare when first described 20 years ago, is now known to be the second most common chronic esophageal disorder known, next to GERD, with a prevalence similar to that of inflammatory bowel disease.


Etiology and pathophysiology

Largely unknown but food allergens are believed to play a role. Histology is characterized by eosinophilic infiltration.


Clinical presentations and complications

Dysphagia and food impaction.


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