No, according to this study:
Conclusion: In conclusion, during ADHF, continuation of beta-blocker therapy is not associated with delayed or lesser improvement, but with a higher rate of chronic prescription of beta-blocker therapy after 3 months, the benefit of which is well established.
In the vast majority of subjects the beta blocker dose was not changed. Patients requiring drugs like dobutamine were excluded.
B-CONVINCED is consistent with an analysis from the OPTIMIZE-HF registry [3], in which maintenance of beta-blocker therapy in systolic ADHF dramatically cut mortality at two to three months (p=0.044), as did starting the drugs at discharge in such patients who hadn't previously been on them (p=0.006). Also as reported by heartwire when the study was published, taking patients off beta blockers at hospitalization more than doubled all-cause mortality (p=0.013).
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