Tuesday, January 12, 2010

Bicarb for prevention of contrast-induced nephropathy

The pendulum is swinging back. According to the latest systematic review:

The effectiveness of sodium bicarbonate treatment to prevent CIN in high-risk patients remains uncertain. Earlier reports probably overestimated the magnitude of any benefit, whereas larger, more recent trials have had neutral results. Large multicenter trials are required to clarify whether sodium bicarbonate has value for prevention of CIN before routine use can be recommended.

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